The right base depends entirely on what you're there for — theme parks, beach and culture, or a classic downtown city stay.
If Ferrari World, Warner Bros. World, Yas Waterworld, SeaWorld Abu Dhabi or the Yas Marina F1 circuit are the point of your trip, staying on Yas Island removes the daily commute entirely. Several hotels sit within walking distance of the parks, and Yas Mall and Yas Bay Waterfront cover shopping and dining without needing a taxi.
Saadiyat suits travellers prioritising the Louvre Abu Dhabi, a genuine beach resort stay, and a quieter pace generally. It's a little further from downtown and Yas Island than either is from each other, so factor in transfer time if you plan to bounce between all three areas.
Staying along the Corniche or in the downtown core puts you closest to Qasr Al Hosn, the older city grid, restaurants outside the resort bubble, and generally better value hotels. It's the most practical base if you want to walk somewhere in the evening rather than relying on a car for everything.
Abu Dhabi's financial district has become a genuine hotel destination in its own right, with design-forward five-star properties, the Galleria mall, and easy access to downtown — a good fit for business travellers or anyone who wants a quieter, more contemporary base.
Yas Island wins for families focused on theme parks; Saadiyat Island suits families who want a calmer beach-and-culture pace with a strong resort pool scene.